Your partner for advanced studies in ecotoxicology and endocrine disruptors

As a leading international player in agronomic and environmental studies, Staphyt, in its Ecotoxicology, Environmental Fate, Phys-Chem laboratory, offers comprehensive, tailor-made solutions in ecotoxicology and endocrine disruptors studies. With recognised scientific expertise and state-of-the-art equipment, our laboratories meet the most stringent regulatory requirements in Europe and beyond.

Ecotoxicology expertise: guaranteeing environmental safety

Our ecotoxicology laboratory specialises in analysing the impact of chemicals, both natural and synthetic, on non-target organisms and ecosystems. Our capabilities include :

Aquatic and terrestrial testing to OECD guidelines (algae, fish, daphnia, earthworms, etc.).
Customisation of test protocols, enabling us to work with complex substances such as volatiles or insolubles.
Testing under Good Laboratory Practice (GLP) for regulatory studies or R&D requirements.

Working closely with our experts in analytical chemistry, we develop and validate unique methods for accurately measuring the concentrations of substances in different media (water, soil, organisms) in accordance with local and international regulations.

Aquatic ecotoxicology studies

List of aquatic ecotoxicology studies:

OECD 201 Growth inhibition assay in freshwater algae and cyanobacteria
OECD 202 Acute immobilisation test, Daphnia sp.
OECD 203 Acute fish toxicity test
OECD 210 Fish early life stage of life toxicity test
OECD 211 Reproduction test, Daphnia magna
OECD 212 Short-term toxicity test, embryo and sac-fry stages in fish
OECD 215 Growth test in juvenile fish
OECD 218 non-radiolabelled Sediment-Water Chironomid Toxicity Using Spiked Sediment
OECD 219 non-radiolabelled Sediment-Water Chironomid Toxicity Using Spiked Water
OECD 221 Growth inhibition test, Lemna sp.
OECD 236 Fish Embryo Acute Toxicity Test
OECD 238 Sediment-Free Myriophyllum Spicatum Toxicity Test
OECD 239 Water-Sediment Myriophyllum Spicatum Toxicity Test

List of terrestrial ecotoxicology studies:

OECD 207 Earthworm, Acute Toxicity Tests
OECD 208 Test on terrestrial plants: seedling emergence and seedling growth test
OECD 209 Activated Sludge, Respiration Inhibition Test (Carbon and Ammonium Oxidation)
OECD 216 Soil micro-organisms: nitrogen transformation test
OECD 217 Soil micro-organisms: Carbon transformation test
OECD 222 Earthworm Reproduction Test (Eisenia fetida/Eisenia andrei)
OECD 227 Test on terrestrial plants: vegetative vigour test
OECD 232 Reproduction test for springtails in soil
Aphidius rhopalosiphi: Mead Briggs et al. 2000 – A laboratory test for evaluating the effects of plant protection products on the parasitic wasp, Aphidius rhopalosiphi (DeStephani-Perez) (Hymenoptera, Braconidae)
OECD 226 Predatory mites reproduction test in soil (Hypoaspis aculeifer)
Typhlodromus pyri: Blümel et al. 2000 – Laboratory residual contact test with the predatory mite Typhlodromus pyri Scheuten (Acari: Phytoseiidae) for regulatory testing of plant protection products
OECD 214: Honeybees, Acute Contact Toxicity Test
OECD 213: Honeybees, Acute Oral Toxicity Test
OECD 237: Honey Bee (Apis Mellifera) Larval Toxicity Test, Single Exposure
OECD 239: Water-Sediment Myriophyllum Spicatum Toxicity Test
OECD 245: Honey Bee (Apis Mellifera L.), Chronic Oral Toxicity Test (10-Day Feeding)
OECD 246: Bumblebee, Acute Contact Toxicity Test
OECD 247: Bumblebee, Acute Oral Toxicity Test

Fate of substances in the environment: a comprehensive analysis

biotransformation studies

Staphyt offers a full range of studies to analyse the fate of substances in the environment, an essential aspect in assessing their environmental safety and regulatory compliance. These studies include :

Biodegradability: Measuring the ability of a substance to break down naturally under controlled conditions.
Biotransformation: Studying the chemical or biological modifications of substances in soils, sediments and water.
Bioaccumulation: Assessing the potential for accumulation in living tissue and its impact on the food chain.

These data provide a better understanding of the interactions between substances and the various compartments of the environment, providing authorities and industry with essential information for minimising environmental risks.

List of Biodegradability studies:

OECD 301 Ready biodegradability (A, B, C, D, E & F)
OECD 302 A Inherent biodegradability: Modified SCAs method
OECD 302 B Intrinsic biodegradability: Zahn-Wellens/EMPA test
OECD 304 Inherent biodegradability in soil
OECD 306 Biodegradability in sea water
OECD 309 non-radiolabelled Aerobic mineralisation in surface water – Simulated Biodegradation Test
OECD 310 Ready biodegradability – CO2 emission in hermetically sealed vessels (Headspace Test)
OECD 311 Anaerobic biodegradability test of organic compounds in digested sludge: measurement of gas production
OECD 314 Simulation tests to assess the biodegradability of chemicals discarded in waste water

List of Biotransformation and Bioaccumulation studies:

OECD 305 non-radiolabelled Bioaccumulation in Fish: Aqueous and Dietary Exposure
OECD 307 non-radiolabelled Aerobic and anaerobic transformation in soil
OECD 308 non-radiolabelled Aerobic and anaerobic transformation in aquatic sediments
OECD 309: Aerobic Mineralisation in Surface Water – Simulation Biodegradation Test
OECD 312 non-radiolabelled Leaching in soil columns

Endocrine disrupters: Identifying the risks for people and the environment

endocrine disruptors studies

Staphyt offers specialised studies to assess whether an active substance has endocrine disrupting properties, in accordance with current regulations (such as Regulation (EC) No 1107/2009). Our services cover

Level 3, 4 and 5 in vivo tests, as recommended by the OECD, to analyse impacts on reproduction, development and other endocrine functions.
Integrated approaches, combining ecotoxicological data and environmental exposure modelling, to provide robust conclusions tailored to the requirements of the regulatory authorities.

List of studies on endocrine disruptors:

OCDE 210: Fish early life stage toxicity test
OCDE 211: Reproduction test, Daphnia magna
OCDE 218: Sediment-Water Chironomid Toxicity Using Spiked Sediment
OCDE 219: Sediment-Water Chironomid Toxicity Using Spiked Water
OCDE 229: Short-term fish reproduction test
OCDE 230: 21-day fish test
OCDE 231: Amphibian metamorphosis assay
OCDE 233: Life cycle toxicity test for Chinonomids in a sediment-water system using spiked water or spiked sediment
OCDE 234: Fish sexual development test
OCDE 240: Medaka extended one generation reproduction test (MEOGRT)
OCDE 241: Larval amphibian growth and development assay (LAGDA)

Why choose Staphyt?

Comprehensive regulatory expertise: Staphyt supports its customers in preparing complete scientific dossiers, risk assessment and scientific justification of data.
Customised solutions: Our teams adapt to the specific needs of each project, proposing tailor-made methods and protocols.
International reach: With laboratories and services in agrosciences and regulatory affairs in several regions, we are able to respond to local requirements while maintaining a global vision.

With Staphyt, you benefit from a partner committed to combining scientific innovation with respect for the environment to deliver sustainable solutions. To find out more and discuss your projects, contact our team: